At KSQ Therapeutics, we are always looking for strong leaders to join our team.
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To be able to manage our flow of candidates we do not accept unsolicited resumes from any source other than directly from the candidates for current or future positions. Submission of unsolicited referrals and/or resumes in advance of a signed agreement between KSQ and the recruiter are deemed gratuitous and KSQ will not be obligated or bound in any way to pay any referral or other fees if such person is hired. Thank you in advance for your adherence to our process. For any hiring needs, please contact us.

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Head of Oncology Clinical Development

The Company

KSQ Therapeutics is pioneering High-Confidence Drug Development: a fundamentally new approach to R&D where the majority of the de-risking work is done prior to the generation of therapeutic drug candidates. Powered by our proprietary CRISPRomics™ drug discovery engine, our team has elucidated the function that each human gene plays in multiple oncology models, providing a unique and more comprehensive understanding of disease biology. The quality of these insights enables our scientists to rapidly identify and validate high-confidence, patient-tailored, novel drug targets and then focus our collective efforts on the development of medicines with the greatest potential to impact the lives of patients. KSQ has a robust pipeline of preclinical discovery programs and was founded in 2015.

The Role
Head of Oncology Clinical Development

KSQ is in search of a talented “physician scientist” with strong oncology skills to serve as the therapeutic area lead for our Oncology portfolio. In this high-visibility role, you will be the global “face and voice” of Oncology both internally and externally for the company, interact directly with the C-level, and lead clinical development strategies from initial translation to pivotal studies and ultimately through regulatory approval.

The person in this role will successfully:

  • Work closely with the basic sciences to provide a clinical perspective into drug discovery efforts, pipeline prioritization, biomarker selection, pre-clinical PK/PD and toxicology assessments.
  • Develop the initial translational strategy for each indication.
  • Direct and oversee the design and implementation of all clinical projects focused on Oncology.
  • Help develop our global regulatory strategy and be a key member of the team representing the program in front of global regulatory agencies.
  • Prepare or assist in the preparation of various official and regulatory documents, for FDA and other regulatory agencies, such as Dossiers, NDAs, INDs, Safety and Annual reports, and handling of responses to official questions about complex safety or efficacy issues.
  • Monitor study implementation and execution, leading the analyses and data evaluation process for progress reporting and presentations to C-Suite, senior leadership and Board of Directors, when appropriate.
  • Work with biostatisticians, key opinion leaders/experts, clinical trial investigators and internal regulatory partners to implement protocols/studies and regulatory submissions.
  • Attend public speaking engagements, including but not limited to:
    • Presentation of data at regional and national advisory boards;
    • Conducting site visits and hospital lectures;
    • Presentation of company and data at financial forums;
    • Regular interactions with key medical opinion leaders
  • Initiate and oversee the safety reporting system for accountable company products to ensure that Serious Adverse Events are properly reported.
  • Ensure the quality and validity of scientific and medical content relating to all clinical programs.
  • In partnership with the KSQ's Leadership Team, develop strategies and implementation plans that achieve the Company's overall goals. Oversee implementation of all such plans to successful execution.
  • Function as a collaborative member of the company's Leadership Team
  • Establish and manage clinical departmental functions, systems, documentation, and procedures for the successful conduct and audit of clinical studies.
  • Build strong executive partnerships with the executive team and other key leaders at KSQ.


The Right Candidate

  • A clinical oncologist who therefore will hold a MD or MD/PhD
  • Strong strategic oncology clinical development skills gained as a PI in a top academic research center or gained in the life sciences industry
  • Strong clinical medical oncology experience
  • Strong emotional intelligence, the ability to build and maintain effective internal and external relationships, and scientific passion.
  • Excellent written and oral communication skills are imperative. Ability to anticipate and adapt to change; strong interpersonal skills commensurate with the need to work closely with partners, investigators, contractors, consultants, and team members across functions
  • Ability to communicate well with health care professionals. Ability to establish strong relationships with peer groups, professional organizations, and other outside parties

Apply Now!