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Director, Head of T Cell Engineering & Process Development

About KSQ Therapeutics

KSQ Therapeutics has built an industry-leading genome-scale precision functional genomics platform, called CRISPRomics, to pinpoint therapeutic nodes that directly correlate genomic function to disease with unprecedented certainty and speed. The company is deploying CRISPRomics for novel drug development across broad therapeutic areas and is advancing a proprietary pipeline of tumor- and immune-focused drug candidates for oncology. KSQ was founded by thought leaders in the field of functional genomics and pioneers of CRISPR screening technologies. The company is in Kendall Square in Cambridge, Massachusetts.


  • Function head in leading an innovative engineered T cell therapy platform into clinical trials, with the goal of commercialization
  • Provide strategic oversight of process development, technical transfer, scale-up
  • Interface and manage internal function teams and external academic and CMO collaborations
  • Plan and perform engineered T cell manufacturing processes
  • Oversight of assays to characterize engineered primary T cells to support product characterization
  • Expertise in in vitro cellular immunology assays, including flow cytometry and molecular characterization
  • Expertise in cutting-edge engineered T cell manufacturing approaches
  • Oversight of protocol and operating procedures for technology transfer
  • Document results for IND enabling studies
  • Develop and deliver scientific presentations and reports in a fast and efficient manner
  • Participate in various aspects of company capability building


Key Qualifications

  • PhD in immunology or related discipline; 10+ years of experience in a biopharmaceutical setting
  • A track-record in process development for T cell therapies under GMP/cGMP manufacturing standards
  • Manufacturing scale-up or technical transfer experience with engineered T cell products
  • A strong publication record in top-tier, peer-reviewed journals
  • Demonstrated ability to evolve, think critically and creatively as part of a fast-paced research team
  • Demonstrated commitment to quality, attention to detail, and team player mentality

Apply Now!