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Associate Scientist, Biotherapeutics Drug Discovery

KSQ Therapeutics, Inc. has an immediate opening for an Associate Scientist, Biotherapeutics Drug Discovery position in Cambridge, MA. KSQ Therapeutics has built an industry-leading genome-scale precision functional genomics platform, called CRISPRomics, to pinpoint therapeutic nodes that directly correlate genomic function to disease with unprecedented certainty and speed. The company is deploying CRISPRomics for novel drug development across broad therapeutic areas and is advancing a proprietary pipeline of tumor- and immune-focused drug candidates for oncology. KSQ was founded by thought leaders in the field of functional genomics and pioneers of CRISPR screening technologies. The company is located in Kendall Square in Cambridge, Massachusetts.

KSQ Therapeutics is seeking an exceptional and highly motivated Associate Scientist to join the Biotherapeutics Drug Discovery group. The successful applicant will work with internal functional groups to help design and execute screening strategies for therapeutic antibody discovery campaigns – including biochemical, molecular, and/or cellular assays for the testing of biotherapeutics from discovery to lead-optimization This is a unique opportunity to learn and develop in a highly dynamic and interdisciplinary environment.


  • B.S./M.S. with 0-3 years of relevant experience in molecular/cellular biology, biochemistry, or a related discipline
  • Experience with mammalian tissue culture required.
  • Experience with standard cell biology experimental design and molecular techniques (western blotting, immunofluorescence, IHC, HTRF etc.) preferred.
  • Excellent verbal and written communication and interpersonal skills for participating across functional groups and externally
  • Demonstrated ability to think critically and creatively as part of a fast-paced research team
  • Demonstrated commitment to quality, attention to detail, and team player mentality
  • Familiarity with standard immunological laboratory techniques.


  • Work with internal functional groups to help develop, optimize and execute high throughout binding assays (ELISA, Octet, FACS) and cell based assays (functional, phenotypic, reporter etc.) for screening panels of therapeutic antibody candidates
  • Document and present experimental data, hypotheses, conclusions and interpretations at company and team meetings
  • Participate in various aspects of this new company from building out the capabilities to contributing to generating data in a fast and efficient manner


A competitive overall compensation package including: competitive base salary, bonus potential and stock options.

Apply Now!