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Associate Scientist/Scientist, Biotherapeutics Drug Discovery

About KSQ Therapeutics

KSQ Therapeutics has built an industry-leading genome-scale precision functional genomics platform, called CRISPRomics, to pinpoint therapeutic nodes that directly correlate genomic function to disease with unprecedented certainty and speed. The company is deploying CRISPRomics for novel drug development across broad therapeutic areas and is advancing a proprietary pipeline of tumor- and immune-focused drug candidates for oncology. KSQ was founded by thought leaders in the field of functional genomics and pioneers of CRISPR screening technologies. The company is located in Kendall Square in Cambridge, Massachusetts.


KSQ Therapeutics is seeking an exceptional and highly motivated Associate Scientist/Scientist to join the Biotherapeutics Drug Discovery group. The successful applicant will work with internal functional groups to help design and execute screening strategies for therapeutic antibody discovery campaigns – including biochemical, molecular, and/or cellular assays for the testing of biotherapeutics from discovery to lead-optimization. This is a unique opportunity to learn and develop in a highly dynamic and interdisciplinary environment.


  • Work with internal functional groups to develop, optimize and execute high throughput binding assays (ELISA, Octet, FACS) and cell-based assays (functional, phenotypic, reporter etc.) for screening panels of therapeutic antibody candidates
  • Isolate, sort, culture, and characterize primary immune cells from human and animal tissues
  • Contribute to various aspects of platform development for the Biotherapeutics group
  • Deliver high-quality data to inform all stages of drug discovery
  • Document and present experimental data, hypotheses, conclusions and interpretations at company and team meetings
  • Participate in various aspects of this new company from building out the capabilities to contributing to generating data in a fast and efficient manner


Key Qualifications

  • B.S./M.S. in biology or a related field, with a minimum of 1-5 years of experience working full-time in a research laboratory in molecular/cellular biology, biochemistry, or a related discipline
  • Industry experience with a drug discovery and/or immunology background highly desirable
  • Experience with cell culture, standard cell biology experimental design, and molecular techniques required
  • Experience with standard immunological laboratory techniques
  • Excellent verbal and written communication and interpersonal skills for participating across functional groups and externally
  • Demonstrated ability to think critically and creatively as part of a fast-paced research team
  • Demonstrated commitment to quality, attention to detail, and team player mentality

Apply Now!