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To be able to manage our flow of candidates we do not accept unsolicited resumes from any source other than directly from the candidates for current or future positions. Submission of unsolicited referrals and/or resumes in advance of a signed agreement between KSQ and the recruiter are deemed gratuitous and KSQ will not be obligated or bound in any way to pay any referral or other fees if such person is hired. Thank you in advance for your adherence to our process. For any hiring needs, please contact us.

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IT Manager

At KSQ Therapeutics, we seek to understand the role of every human gene in each disease, each tissue, and each cell that we study. This comprehensive approach has resulted in a massive, experimentally derived dataset that we have found to be remarkably predictive of past successes and failures in oncology and immuno-oncology product development. Utilizing this approach, we also identified a number of opportunities for the development of new medicines. As a result, we have aggressively invested in these distinct, highly validated pathways for new drug development with the expectation that the medicines we create may become the next breakthrough products for patients.

Founded in late 2015, KSQ is a clinical-stage biotech that has rapidly advanced the field of CRISPR-enabled functional genomics, from in vitro cell autonomous screens to more complex genome-scale screens of immune cells in vivo. The company has expanded the scope of its technology to include multiple cell types and to unlock areas beyond oncology. KSQ is led by a team of accomplished industry experts in drug discovery and development.

Position Summary:

KSQ is seeking a Manager of IT Operations to manage and build on our well-established information technology function. As the first internal contact of the company's IT operations, you will collaborate closely with colleagues, senior management, and other stakeholders to assess user needs and ensure success of IT Managed Services. This is a high impact, high visibility role! You will work cross-functionally to find, implement, and continuously improve practical and scalable technology solutions. In this role, you will have the opportunity to be a part of a fast-paced, deeply scientific, and friendly clinical-stage biotech environment. KSQ values its employees and prides itself on its unique culture. This role reports to the Director of Operations and IT but will work with ALL departments across the organization. You may be the right fit if you foster positive employee relations and a culture of continuous improvement, partnership and teamwork. While technical aptitude is appreciated, we deeply value soft skills such as creativity, interpersonal, written and communication skills.



Operational Management

  • Manage and assist in the day-to-day operations of on-site and remote IT support, including provisioning end-user services such as help desk and technical support.
  • Manage the deployment, monitoring, maintenance, development, upgrade, and support of all IT systems, including servers (on premise and cloud), PCs, operating systems, hardware, software, and peripherals.
  • Administrate all technology services, including communication & collaboration platforms (O365, Teams, Zoom, Smartsheet, Egnyte, etc.)
  • Responsible for asset management of IT hardware, software, and equipment.
  • Coordinate with IT MSPs to measure availability, performance, capacity, and utilization of IT and Informatics services.
  • Manage and contribute to major aspects of compliance (SOX, 21 Part 11, Privacy)

Strategy and Planning

  • Manage IT department operational planning and projects and organize and negotiate the allocation of IT resources.
  • Work collaboratively with IT teams, internal business partners and external vendors to identify, understand, implement and support new business capabilities, optimize processes and drive operational efficiency
  • Collaborate on cybersecurity program development and execution
  • Work with stakeholders to define business and systems requirements for new technology implementations.
  • Oversee all reports and documentation related to network and systems operations.
  • Work collaboratively to oversee and implement all IT policies, procedures and plans for security, data center, desktops and infrastructure based on industry-standard best practices.
  • Analyze existing operations and make recommendations for the improvement and growth of the network infrastructure and IT systems.
  • Conduct research and make recommendations on technology solutions and implementations to meet business and system requirements.
  • This is a role based in Lexington, MA with a hybrid work from home model; minimum 3 days a week onsite.

Key Qualifications:

  • BS Degree in computer science or related technical discipline and/or 5+ years experience with IT infrastructure and support.
  • Experience with an out-sourced IT model in the biotech/pharmaceutical industry is preferred but a person who can work autonomously on projects and be willing and able to adapt to new responsibilities is much more important.
  • Well-versed in Microsoft technologies, AWS, Windows, macOS, and Linux
  • Knowledge about cloud concepts such as SaaS, IaaS and PaaS, as well as integration of cloud systems
  • In depth knowledge regarding cybersecurity and data privacy concepts
  • Demonstrated problem-solving and decision-making capabilities
  • Demonstrated leadership and personnel/project management skills.
  • Entrepreneurial and ability to work in a fast-paced, agile, creative and high-growth company environment
  • Experience with and able to communicate technical terms to non-technical colleagues
  • Approachable, responsive and able to proactively communicate risks, issues and recommendations
  • Strong interpersonal skills with a “seek to understand” mentality and strong customer service orientation

KSQ Therapeutics is proud to be an Equal Opportunity Employer.
COVID-19 vaccination is a condition of employment at KSQ, subject to reasonable accommodation where required by law. Employees must be fully vaccinated by date of hire to be considered.

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