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Associate Scientist/Scientist, Target Discovery

At KSQ Therapeutics, we seek to understand the role of every human gene in each disease, each tissue, and each cell that we study. This comprehensive approach has resulted in a massive, experimentally derived dataset that we have found to be remarkably predictive of past successes and failures in oncology and immuno-oncology product development. Utilizing this approach, we also identified a number of opportunities for the development of new medicines. As a result, we have aggressively invested in these distinct, highly validated pathways for new drug development with the expectation that the medicines we create may become the next breakthrough products for patients.

Founded in late 2015, KSQ is a Clinical-stage biotech that has rapidly advanced the field of CRISPR-enabled functional genomics, from in vitro cell autonomous screens to more complex genome-scale screens of immune cells in vivo. The company has expanded the scope of its technology to include multiple cell types and to unlock areas both within Oncology and beyond. KSQ is led by a team of accomplished industry experts in drug discovery and development.


Position Summary:

KSQ Therapeutics, Inc. is seeking a highly motivated scientist to apply their experience in molecular biology towards the discovery of next generation cancer cell therapies. This skilled scientist will help develop novel gene-editing strategies to enhance our eTIL programs. This is an opportunity to learn, contribute across the company, and flourish in KSQ’s dynamic, highly interdisciplinary, and collaborative environment.


  • Associate Scientist: BS degree with 1-3 years of industry experience / Scientist: MS degree preferred with 2-4+ years of industry experience in molecular biology required
  • Experience with modern techniques including CRISPR for genetic engineering and assaying gene function a must (NGS, ddPCR, qPCR, molecular cloning, tissue culture, flow cytometry)
  • Experience in gene editing in cell therapies a big plus
  • Independently developed and applied unique NGS methods or in vitro assays to characterize immuno-oncology targets
  • Demonstrated agility, excellent verbal/written communication, and interpersonal skills to work across functions and with collaborators
  • Assist in querying novel technologies and mechanisms for therapeutic intervention
  • The successful candidate will work as part of an interdisciplinary team contributing to the design and execution of experiments that support our research activities and project goals

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