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Associate Scientist/Senior Associate Scientist, Pharmacology

About KSQ Therapeutics

KSQ Therapeutics has built an industry-leading genome-scale precision functional genomics platform, called CRISPRomics, to pinpoint therapeutic nodes that directly correlate genomic function to disease with unprecedented certainty and speed. The company is deploying CRISPRomics for novel drug development across broad therapeutic areas and is advancing a proprietary pipeline of tumor- and immune-focused drug candidates for oncology. KSQ was founded by thought leaders in the field of functional genomics and pioneers of CRISPR screening technologies. The company is located in Kendall Square in Cambridge, Massachusetts.

Position Summary

KSQ Therapeutics, Inc. is seeking an exceptional and highly motivated Associate Scientist/Senior Associate Scientist to join the Pharmacology group. The successful applicant will contribute to in vivo pharmacology efforts to support the advancement of our pre-clinical Oncology and Immuno-Oncology small and large molecule pipeline. This is a unique opportunity to learn and develop in a highly dynamic and interdisciplinary environment.


  • Independently execute on a wide variety of in vivo techniques across multiple projects with delivery of high quality data
  • Work collaboratively within department and across departments to effectively achieve project goals and timelines
  • Work enthusiastically as part of an interdisciplinary team


  • B.S. with 2+ years of experience in Pharmacology in an industry setting
  • Demonstrated experience in organization and execution of in vivo studies to evaluate tolerability, efficacy and mechanism of action of therapeutic agents.
  • In vivo oncology experience including cell culture, compound preparation and administration (e.g. i.v., s.c, p.o.), tumor xenograft implantation and tumor caliper measurement
  • Experience with immune-oncology in vivo syngeneic models preferred
  • Experience with multiple methods of sampling, including ex vivo tissue processing preferred
  • Excellent experimental documentation, as well as verbal and written communication skills, and an aptitude for the delivery of well-structured scientific presentations
  • Demonstrated ability to think critically and creatively as part of a fast-paced research team
  • Demonstrated commitment to quality, attention to detail, outstanding organizational skills, and team player mentality
  • Understand and implement applicable regulations around animal care/safety/handling

Apply Now!