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Associate Scientist/ Scientist, Oncology Discovery

Job Reference: #018

KSQ Therapeutics, Inc. has multiple openings for Associate Scientist / Scientist, Oncology Discovery positions in Cambridge, MA. KSQ Therapeutics has built an industry-leading genome-scale precision functional genomics platform, called CRISPRomics, to pinpoint therapeutic nodes that directly correlate genomic function to disease with unprecedented certainty and speed. The company is deploying CRISPRomics for novel drug development across broad therapeutic areas and is advancing a proprietary pipeline of tumor- and immune-focused drug candidates for oncology. KSQ was founded by thought leaders in the field of functional genomics and pioneers of CRISPR screening technologies. The company is located in Kendall Square in Cambridge, Massachusetts.

Position Summary

KSQ Therapeutics, Inc. is seeking an exceptional and highly motivated Associate Scientist / Scientist: Oncology Discovery to apply their experience in oncology towards the discovery of the next generation of impactful therapies.  This person will contribute to cell biology and translational efforts for our discovery pipeline. This skilled scientist will characterize novel cancer pathways and develop assays for drug targets. She/he must be driven and flexible with the broad number of in vitro, in vivo, and biomarker activities associated with cancer discovery. This is your opportunity to learn, contribute and flourish in KSQ’s dynamic, highly interdisciplinary, and collaborative environment.  If you’re driven, the next stage of your career may be at KSQ!

Key Qualifications

  • Associate Scientist: BS degree with 0-3 years of industry experience / Scientist: MS degree preferred with 4+ years of oncology drug discovery required
  • Demonstrated expertise in cancer research with relevant assays and approaches needed
  • Excellent verbal and written communication and interpersonal skills to work across functions and with collaborators
  • Experience with modern techniques for assaying gene function and pathway biology (CRISPR, RNAi, high content imaging, MSD, FACS, in vivo etc), a big plus
  • Ability to think critically and creatively as part of a fast-paced research team.
  • Commitment to yourself, the Team, and to helping patients is a must.


  • Assist in querying novel pathways and mechanisms for therapeutic intervention
  • Develop and apply unique assays to identify and characterize novel targets, with a focus on in vitro assays (qPCR, westerns, IF, serum shift, hepatocyte stability, HTRF etc.)
  • The successful candidate will work as part of an interdisciplinary team contributing to the design and execution of experiments that support our research activities and project goals
  • Participate in various aspects of this new company from building out the capabilities to contributing to generating data in a fast and efficient manner


A competitive overall compensation package including: competitive base salary, bonus potential and stock options.


To learn more about this exciting career opportunity, please forward your resume and background information in confidence to Dr. Michael Lam at Please refer to the Job Reference Number and Job Title in the email subject.